Research Associate

Tiegang Xu

Title: Professor Associate
Subject:  Biosensor
Phone: +86-021-62511070
Fax: +86-021-62131744
Email: tiegangxu@mail.sim.ac.cn
Address: 865 Changning Road, Shanghai,China, 200050

RESUME

Dr Tiegang Xu received his Ph.D. in Microbiology in Shanghai Jiao Tong University, and his B.S. in Biochemistry and Molecular biology in Nankai University. He researched in DNA phosphorothioation for his Ph.D study, and found an unusual phosphorothioation-dependent restriction modification system from Salmonela. Then he worked in Shanghai institute of Microsystem and Information Technology, CAS, and researched in biosensors based on microcantilever and microfluidic system for pathogens detection, disease diagnosis and cell analysis. He hosted a project of National Natural Science of China and hosts a project of Shanghai Natural Science Foundation.

SELECTED PUBLICATIONS

1)Yu H, Chen Y, Xu P, Xu T, Bao Y, Li X.. 2016 μ-'Diving suit' for liquid-phase high-Q resonant detection. Lab Chip, 165,902-910, 

2)Xue C., Yang C., Xu T., Zhan J., Li X.. 2015. A wireless biosensing microfluidic-chip based on resonating ‘μ-diver’. Lab Chip, 15(10),2318-2326,

3)Xu T., Yu H., Xu P., Xu W., Chen W., Chen C., Li X.. 2014. Real-time enzyme-digesting identification of double-strand DNA in a resonance-cantilever embedded micro-chamber. Lab Chip, 14(6),1206-1214,

4)Xu P., Li X., Yu H., Xu T.. 2014. Advanced Nanoporous Materials for Micro-Gravimetric Sensing to Trace-Level Bio/Chemical Molecules. Sensors, 14(10): 19023-19056,

5)Xia X, Guo S., Zhao W., Xu P., Yu H., Xu T., Li X.. 2014. Carboxyl functionalized gold nanoparticles in situ grown on reduced graphene oxide for micro-gravimetric ammonia sensing. Sensor Actuat B-Chem, 202: 846-853

6)Xu T., Yu H., Xu P., Li X..2012 A chelating-bond breaking and re-linking technique for rapid re-immobilization of immune micro-sensors. Biomed Microdevices 14(2):303-1

7)Tao Y., Li X., Xu T., Yu H., Xu P., Xiong B., Wei C.. 2011. Resonant cantilever sensors operated in a high-Q in-plane mode for real-time bio/chemical detection in liquids. Sensor Actuat B-Chem 157(2), 606-614,

8)Xu T., Yao F., Zhou X., Deng Z., You D.. 2010. A novel host-specific restriction system associated with DNA backbone S-modification in Salmonella. Nucleic Acids Res. 38(20), 7133-7141,

9)Xu T., Liang J., Chen S., Wang L., He X., You D., Wang Z., Li A., Xu Z., Zhou X., Deng Z.. (2009). DNA phosphorothioation in Streptomyces lividans: Mutational analysis of the dnd locus. BMC Microbiol  9(41),

10)Yao F., Xu T., Zhou X., You D., Deng Z. 2009. Functional analysis of spfD gene involved in DNA phosphorothioation in Pseudomonas fluorescens Pf0-1. FEBS Lett.  4 (583): 729-733,

11)You D., Xu T., Yao F., Zhou X., Deng Z.. 2008. Direct evidence that ThiI is an ATP pyrophosphatase for the adenylation of uridine in 4-thiouridine biosynthesis. Chembiochem,. 9(12): 1879-82,

12)Wang L., Chen S., Xu T., Taghizadeh K., Wishnok J., Zhou X., You D. Deng Z., Peter C. D. 2007. Phosphorothioation of DNA in bacteria by dnd genes. Nat Chem Biol, 3(11): 709-710,

13)Zhou X., He X., Liang J., Li A., Xu T., Kieser T., John D. H., Deng Z.. 2005. A novel DNA modification by sulphur. Mol Microbiol,. 57(5): 1428-38,

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